|Keck Seminar: A Mass Spectrometry Perspective on Protein Systems: Lessons from a Human Neuroendocrine Cell|
Steven Bark, PhD, Assistant Professor, Biology & Biochemistry, University of Houston
|date:||4:00PM US Central (GMT −0600)|
Friday, March 15, 2013
|location:||BRC Auditorium, BioScience Research Collaborative Building, Rice University|
|sponsor:||Gulf Coast Consortia|
Adrenal chromaffin cells of the sympathetic nervous system have been used for over 40 years as the model neuronal and neuroendocrine cell. Chromaffin cells secrete small molecule neurotransmitters (catecholamines and dopamine) and neuropeptides (enkephalins and endorphins) that regulate critical biological processes including energy homeostasis, blood pressure, pain, and stress response. Secretion from neuroendocrine cells occurs primarily through dense-core secretory vesicles (DCSVs), which package neurotransmitters and neuropeptides and secrete upon stimulation. Despite the critical importance of this secretory system, almost all previous studies have used DCSVs isolated from bovine or rodent species. Our knowledge of the human secretory organelle is limited.
|more info:||Gulf Coast Consortia for Quantitative Biomedical Sciences|
|watch:||There is no archive media for this event.|
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